| | | Squads | Games | Starts | Sub On |
| >6 matches | 204 | 32 | 480 | 116 |
| 1 | Gethin Jenkins | 3 | 15 | 10 | 5 |
| 2 | Gareth Thomas | 4 | 14 | 11 | 3 |
| 3 | Stephen Jones | 4 | 13 | 7 | 6 |
| 4 | Adam Jones | 3 | 12 | 10 | 2 |
| 5 | Alun Wyn Jones | 2 | 11 | 9 | 2 |
| 6 | Shane Williams | 3 | 11 | 11 | 0 |
| 7 | Colin Charvis | 3 | 11 | 10 | 1 |
| 8 | Ieuan Evans | 3 | 11 | 11 | 0 |
| 9 | Mike Phillips | 2 | 10 | 7 | 3 |
| 10 | Martyn Williams | 3 | 10 | 8 | 2 |
| 11 | Robert Jones | 3 | 10 | 10 | 0 |
| 12 | Huw Bennett | 3 | 9 | 6 | 3 |
| 13 | James Hook | 2 | 9 | 7 | 2 |
| 14 | Dwayne Peel | 2 | 8 | 4 | 4 |
| 15 | Mark Taylor | 2 | 8 | 7 | 1 |
| 16 | Gareth Llewellyn | 3 | 8 | 7 | 1 |
| 17 | Garin Jenkins | 3 | 8 | 7 | 1 |
| 18 | Luke Charteris | 1 | 7 | 6 | 1 |
| 19 | Bradley Davies | 1 | 7 | 3 | 4 |
| 20 | Taulupe Faletau | 1 | 7 | 7 | 0 |
| 21 | Jonathan Davies (CE) | 1 | 7 | 6 | 1 |
| 22 | George North | 1 | 7 | 6 | 1 |
| 23 | Mark Jones | 2 | 7 | 7 | 0 |
| 24 | Scott Gibbs | 2 | 7 | 7 | 0 |
| 25 | Neil Jenkins | 2 | 7 | 7 | 0 |
